Ardelyx (ARDX) has quietly established itself as one of the crucial fascinating biotech tales, buying and selling at beneath $10. With two FDA-approved therapies available on the market, IBSRELA and XPHOZAH, delivering constant progress, Ardelyx is not only one other speculative clinical-stage biotech. It’s constructing a sustainable business enterprise in specialty medication.
The corporate’s second-quarter outcomes confirmed a sort of momentum hardly ever seen in small-cap biotech.
Valued at $1.5 billion, ARDX inventory has returned 422% over the previous three years and 21.5% year-to-date (YTD). Nonetheless, Wall Road feels this under-$10 inventory has the potential to extend 141% from its present ranges.
Ardelyx is a biotech firm centered on discovering, creating, and commercializing first-in-class medicines that concentrate on cardiovascular and kidney illnesses. It presently has two commercially accessible merchandise and is creating others. IBSRELA (tenapanor) is used to deal with adults with irritable bowel syndrome with constipation (IBS-C). In the meantime, XPHOZAH (tenapanor) is used to deal with sufferers with persistent kidney illness (CKD) who require dialysis and have hyperphosphatemia (excessive phosphate ranges).
Within the second quarter, Ardelyx reported complete income of $97.7 million, up 33% from $73.2 million within the year-ago quarter. This progress was fueled principally by IBSRELA gross sales and product provide income from worldwide companions. Collaboration and provide gross sales generated greater than $6 million, diversifying the highest line.
Notably, IBSRELA web product gross sales reached $65 million, up 84% year-on-year (YoY). Affected person demand stays constant, and prescription pull-through has improved. Primarily based on this momentum, Ardelyx boosted its full-year 2025 gross sales projection to $250 million to $260 million, a big step towards assembly peak gross sales expectations of greater than $1 billion. In the meantime, XPHOZAH gross sales fell to $25 million in Q2 from $37.1 million in the identical interval final yr, owing to the lack of Medicare protection, however elevated by 7% sequentially. Nonetheless, administration sees encouraging indicators that XPHOZAH’s market technique is gaining traction, with peak gross sales potential estimated at $750 million.
Ardelyx (ARDX) has quietly established itself as one of the crucial fascinating biotech tales, buying and selling at beneath $10. With two FDA-approved therapies available on the market, IBSRELA and XPHOZAH, delivering constant progress, Ardelyx is not only one other speculative clinical-stage biotech. It’s constructing a sustainable business enterprise in specialty medication.
The corporate’s second-quarter outcomes confirmed a sort of momentum hardly ever seen in small-cap biotech.
Valued at $1.5 billion, ARDX inventory has returned 422% over the previous three years and 21.5% year-to-date (YTD). Nonetheless, Wall Road feels this under-$10 inventory has the potential to extend 141% from its present ranges.
Ardelyx is a biotech firm centered on discovering, creating, and commercializing first-in-class medicines that concentrate on cardiovascular and kidney illnesses. It presently has two commercially accessible merchandise and is creating others. IBSRELA (tenapanor) is used to deal with adults with irritable bowel syndrome with constipation (IBS-C). In the meantime, XPHOZAH (tenapanor) is used to deal with sufferers with persistent kidney illness (CKD) who require dialysis and have hyperphosphatemia (excessive phosphate ranges).
Within the second quarter, Ardelyx reported complete income of $97.7 million, up 33% from $73.2 million within the year-ago quarter. This progress was fueled principally by IBSRELA gross sales and product provide income from worldwide companions. Collaboration and provide gross sales generated greater than $6 million, diversifying the highest line.
Notably, IBSRELA web product gross sales reached $65 million, up 84% year-on-year (YoY). Affected person demand stays constant, and prescription pull-through has improved. Primarily based on this momentum, Ardelyx boosted its full-year 2025 gross sales projection to $250 million to $260 million, a big step towards assembly peak gross sales expectations of greater than $1 billion. In the meantime, XPHOZAH gross sales fell to $25 million in Q2 from $37.1 million in the identical interval final yr, owing to the lack of Medicare protection, however elevated by 7% sequentially. Nonetheless, administration sees encouraging indicators that XPHOZAH’s market technique is gaining traction, with peak gross sales potential estimated at $750 million.

















